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R-thalidomide drug molecule, computer model
Description:
Thalidomide (C13.H10.N2.O4) molecular model. The atoms are color-coded: carbon (yellow), hydrogen (white), nitrogen (green) and oxygen (pink). This is R-thalidomide, a mirror image (enantiomer) of S-thalidomide, both of which share the same structural formula. Thalidomide was developed as a sedative drug to aid sleep in pregnant woman. It was found to cause fetal abnormalities (stunted limbs, or phocomelia), and was withdrawn in 1961. Further research discovered that only the 'S' form caused deformities. A purified drug containing only the 'R' enantiomer is now being used to treat leprosy and as an anti-cancer drug. See A624/154 for an image of S-thalidomide.
Credit:
Dr. Tim Evans/Science Source
Unique identifier:
SS293264
Legacy Identifier:
SB5127
Type:
Image
Size:
4000px × 3000px (~34 MB)
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Tags
A624/0158
A624/158
A6240158
antineoplastic
art
atomic
atoms
ball and stick
balls
biochemistry
birth defects
chemistry
complications
compound
compounds
drug
enantiomer
horizontal
hypnosis
leprosy
model
molecular
molecule
molecules
pharmaceutical
pharmaceutics
phocomelia
pregnancy
r
r-thalidomide
sedative
sleeping
sticks
structural
structure
teratogen
thalidomide